Assignment of two isoforms of the AMP-activated protein kinase gamma subunits, PRKAG1 and PRKAG2 to porcine chromosomes 5 and 18, respectively by radiation hybrid panel mapping.
نویسندگان
چکیده
Assignment of the ovine uroporphyrinogen decarboxylase (UROD) gene to chromosome 1p34→p36 by fluorescence in situ hybridization R. Nezamzadeh,a J. Habermann,b R. Fries,b and B. Breniga a Institute of Veterinary Medicine, Georg-August-University of Goettingen, Goettingen (Germany); b Chair for Animal Breeding and Genetics, WZW Technical University of Munich, Weihenstephan (Germany) Cytogenet Genome Res 106:142C (2004) DOI: 10.1159/000078575
منابع مشابه
Assignment1 of two isoforms of the AMP-activated protein kinase Á subunits, PRKAG1 and PRKAG2 to porcine chromosomes 5 and 18, respectively by radiation hybrid panel mapping
The AMP-activated protein kinase (AMPK) is a heterotrimeric enzyme complex comprising catalytic ·-subunits and regulatory ßand Á-subunits (Hardie et al., 2003). Each subunit exists as different isoforms encoded by two or three genes (·1, ·2, ß1, ß2, Á1, Á2, Á3). AMPK has a key role in the regulation of energy metabolism in eukaryotic cells. AMPK is regulated by phosphorylation on the ·-subunit ...
متن کاملAssignment of protein kinase, AMP-activated,beta 2 non-catalytic subunit (PRKAB2) gene to porcine chromosome 4q21 23 by somatic cell and radiation hybrid panel mapping.
PRKAB2 (protein kinase, AMP-activated, beta 2 non-catalytic subunit) belongs to a protein kinase family that has a key role in regulation of energy metabolism in eukaryotic cells. PRKAB2 is activated by an increase in the ratio of adenosine monophosphate to adenosine triphosphate. Activated PRKAB2 turns on ATP producing pathways and inhibits ATPconsuming pathways (Thornton et al., 1998). PRKAB2...
متن کاملRadiation hybrid mapping of the porcine AMPD 1 , PKLR and CHRNB 2 genes to chromosome 4
ree porcine genes, AMPD1 (encoding muscle isoform of adenosine monophosphate deaminase), PKLR (encoding liver and red blood cell isozymes of pyruvate kinase) and CHRNB2 (encoding neuronal nicotinic acetylcholine receptor, beta 2 polypeptide), were assigned to the radiation hybrid map of chromosome 4 using PCR amplification on clones of the IMpRH panel. PKLR was mapped between markers SW270 and...
متن کاملAssignment of the porcine FUS1 gene to SSC13q21q22 by somatic cell and radiation hybrid panel mapping.
FUS1 is a candidate tumor suppressor gene organized in a 370 kb region which contains a set of 19 genes. The human FUS1 genomic sequence spans 3.3 kb containing 3 exons (NM_007275; Lerman and Minna, 2000). Overexpression of the FUS1 gene leads to G1 arrest and growth inhibition of lung cancer cells (Kondo et al., 2001). The human and the murine FUS1 genes were assigned to chromosome HSA3p21.3 a...
متن کاملThe Effect of Eight Weeks Aerobic and Resistance Training on AMP-Activated Protein Kinase (AMPK) Gene Expression in Soleus Muscle and Insulin Resistance of STZ-Induced Diabetic Rat
Background: AMPK regulation is one of biggest target in T2D and metabolic syndrome research. Therefore, the present study is aimed to investigate The effect of 8 weeks aerobic and Resistance training on AMP-activated protein kinase (AMPK) gene expression in soleus muscle and insulin resistance of STZ-induced diabetic rat. Methods: The research method of present study was experimental. For this...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cytogenetic and genome research
دوره 106 1 شماره
صفحات -
تاریخ انتشار 2004